Tweet Group

Jan 12

Bill Hanage @BillHanage - Wed Jan 13
There is a new ‘variant’ clearly identified today, P.1. And it is worth saying a little about what we have learned about it, and from the variants we have identified so far…
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CADDE Project @CaddeProject - Tue Jan 12
**Genomic characterization of an emergent SARS-CoV-2 lineage in Manaus: preliminary findings** New lineage circulating in Manaus, named P.1, has a unique constellation of mutations, including some w potential biological importance 😷🦠🧬. Read here👇…
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Nextstrain @nextstrain - Wed Jan 13
With multiple convergent mutations of biological relevance in spike along with evidence of high frequency in Manaus, we have decided to label the emerging variant described by @caddeproject here… as Nextstrain clade 20J/501Y.V3. 1/2
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Adam Kucharski @AdamJKucharski - Tue Jan 12
Worth reading this analysis of new SARS-CoV-2 variant in Manaus by @nmrfaria & co. Shares mutations with new variants in UK and South Africa (although arose independently). Found in 0/26 samples collected Mar–Nov 2020, but in 13/31 (42%) collected mid-Dec:…
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ɪᴀɴ ᴍ. ᴍᴀᴄᴋᴀʏ, ᴘʜᴅ 🦠🤧🧬🥼🦟🧻 @MackayIM - Wed Jan 13…
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Jeremy Farrar @JeremyFarrar - Tue Jan 12
Important report. Manaus largest city in Amazon region severely hit COVID-19 pandemic with estimated SARS-CoV-2 attack rate ~75% by Oct 2020. Still suffering & where new variants may emerge & transmit despite high seroprevalence & presumed immunity.…
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Ch. Julian Villabona-Arenas @Chjulian - Tue Jan 12
Actualización: El estudio liderado por @nmrfaria @CaddeProject muestra q 42% (13/31) de muestras del estado del Amazonas brasileño (15-23 de dic) hacen parte de un linaje descendiente de B.1.1.28 que contiene varias mutaciones de importancia biológica 1/3…
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Eric Topol @EricTopol - Tue Jan 12
It's not good when the new variant list is expanding ✓ B.1.1.7 "UK" more transmissible ✓ 501Y.V2 "South African" More transmissible, E484K has ? antibody interference ✓ P.1 Manaus (Brazil)… ✓? Japan variant… lots of overlap
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