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Apr 07

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AstraZeneca’s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low platelets - European Medicines Agency

AstraZeneca’s COVID-19 vaccine: EMA finds possible link to very rare cases of unusual blood clots with low platelets
https://www.ema.europa.eu/en/news/astrazenecas-covid-19-vaccine-ema-finds-possible-link-very-rare-cases-unusual-blood-clots-low-blood

EU Medicines Agency @EMA_News - Wed Apr 07

EMA’s safety committee (#PRAC) has concluded its review of very rare cases of unusual blood clots with AstraZeneca #COVID19 vaccine. 👉ema.europa.eu/en/news/astraz… pic.twitter.com/aeyzK3bfxd

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Kai Kupferschmidt @kakape - Wed Apr 07

EMA press release is here, basically concludes: - unusual blood clots with low blood platelets should be listed as very rare side effects of the vaccine - overall benefits of the vaccine in preventing COVID-19 outweigh the risks of side effects - HIT-like mechanism is plausible twitter.com/ema_news/statu…

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BK Titanji #ILookLikeAScientist @Boghuma - Wed Apr 07

EMA concludes in their report that while these rare AEs are likely linked to A/Z 💉and VIPIT a plausible mechanism, benefits of vaccination still outweigh these risks. twitter.com/EMA_News/statu…

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BK Titanji #ILookLikeAScientist @Boghuma - Wed Apr 07

UK's JCVI in light of this review and emerging pharmacovigilance data now recommending use of an alternative #covid19 vaccine other than #AstraZeneca vaxx in individuals <30 y/o. gov.uk/government/pub…

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Dr Michelle Ananda-Rajah @rajah_mich - Wed Apr 07

222/ 34mill, about 1 per 100000. They haven’t issued age restrictions but left countries to impose their own (which a growing list have done). No risk factors identified meaning no way to predict twitter.com/EMA_News/statu…

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Hilda Bastian, PhD @hildabast - Wed Apr 07

EMA is listing unusual blood clots with low platelets as a side effect of the AstraZeneca Covid vaccine ema.europa.eu/en/news/astraz…

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2 expert retweets

Greg Dore @GregDore2 - Wed Apr 07

Key findings from EMA review: 👉 62 CVST & 24 splanchnic (abdominal) vein thrombosis events from 25M AstraZeneca doses 👉 18 (21%) deaths 👉 benefits continue to outweigh risk So, risk around 1/300K & death 1/1.4M, but need age-specific risks. ema.europa.eu/en/news/astraz…

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